Functional Assessment of Quality of Life Using EORTC QLQ-CR29 in Patients with Colon Cancer at King Abdulaziz University Hospital

Colorectal cancer is the third most common cancer in the world. Quality of life is important to achieve successful treatment outcomes.

The aim of this study was to assess the functional quality of life of patients with newly diagnosed colorectal cancer in order to improve our understanding as physicians of how cancer therapy influences the patients’ lives, and how we can help patients improve the quality of life on a daily basis.

This was a cross-sectional study conducted between January-September 2013, of a sample of 647 patients newly diagnosed with colon cancer at the King Abdulaziz University Hospital, Jeddah, Saudi Arabia.

PDF LINK

Metaplastic Breast Cancer and p16 Positivity: What Does It Mean?

Metaplastic breast cancer is a heterogeneous group of malignant breast tumors having different morphologic subtypes. Considerable variations exist in different ethnic groups.

The incidence of metaplastic breast cancer is reported to be 0.2-1 percent of breast cancer and it is rare in the west.

MBC is referred to tumor when conventional breast carcinoma contains a metaplastic component ranging from <10% - >50%

PDF LINK

Mysterious Prostate Cancer Affects More Men than Women

Cancer is the primary cause for death in the world with 14 million cases and 8.2 million deaths annuallys.

Though the reasons are not clearly known, prostate cancer affects increasing number of men and age, ethnicity and family history are some of the factors considered responsible for it.

Occupations like farming, exposure to pesticides, wood dust, grain dust, asbestos dust, tobacco, irregular diet, obesity and low physical activity are responsible for it.

PDF LINK

Calendula officinalis Extracts Protect against H2O2 Induced Chromosome Damage on HacaT Human Skin Cells

Calendula officinalis extracts contain antioxidant compounds. The extracts tested in the current study protect against reactive oxygen species (ROS) induced cytotoxic activity towards human cells.

Objective: To determine the ability of Calendula officinalis extracts to protect against H2O2 induced chromosome damage on HaCaT human skin cells.

Methodology: The chromosome damage protection by four Calendula officinalis extracts was investigated in vitro using a dose-response (0.125, 0.5 and 1.0% (v/v)) on HaCaT human skin cells.

PDF LINK

Cancer, a Multigenic Disease Requires Nature Derived Multi-targeted Drugs

Cancer is a term characterized by the uncontrolled growth and spread of cells leading to invasion of normal tissues. Cancer develops due to the changes caused to normal cells to acquire abnormal functions.

Inherited mutations or environmental factors like, X-rays, chemicals, ultraviolet light, etc are the changes that lead to cancer. So, these facts suggest that cancer is not a result of a single factor.

It typically, takes many years to elapse for normal cells to evolve into cancerous cells. In 2012, according to the WHO, the global cancer burden accounted for 14.1 million new cases and 8.2 million deaths.

PDF LINK

Extraskeletal Osteochondroma of the Heel: A Case Report

Osteochondroma is the most common benign bone tumor and usually occurs in the metaphyseal region of the long bones around the knee.

This is acartilage-capped bony tumor, which out growths on the surface of the bone. Extraskeletal osteochondroma is a variant of extraskeletal chondromas that are uncommon soft-tissue cartilaginous tumors.

This report describes thecase of a 56-year-old woman with an extraskeletal osteochondroma of the heel.

PDF LINK

Laparoscopic Surgery for Large Ovarian Cysts- Review

Laparoscopic surgery has been increasingly applied to different gynecologic problems with excellent surgical outcome and rapid recovery.

Large ovarian cysts, a relatively common gynecologic problem, pose certain challenges to laparoscopic management.

The aim of the present study was to review published reports on laparoscopic surgery for large ovarian cysts and summarize their findings regarding patients’ selection, surgical outcome, technical methods and the final pathology report.

PDF LINK