Misdiagnosis of Groove Pancreatitis: A Case Report

Groove Pancreatitis (GP) is a kind of chronic pancreatitis with a clear pathological diagnosis. It’s characterized by fibrotic scarring of the gastroduodenal groove, an anatomical area near the pancreatic head, duodenum and common bile duct (CBD).

Its etiology is not clear. GP may be related to alcoholism, weight loss, biliary tract disease, pancreatic cysts and so on. Its incidence rate of GP is low and the diagnosis is difficult.

The purpose of this essay is to report a case of GP. A 56-year-old woman is admitted to hospital with painless systemic jaundice as her only symptom and the symptom aggravated in two months.

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Adjuvant Chemoradiation for Localized Gastric Adenocarcinoma: An Institutional Experience

cancer with locoregional relapse in 40% to 60%. The frequency of relapses makes regional radiotherapy an attractive possibility for adjuvant therapy. The survival benefit of adjuvant chemoradiation over surgery alone was first established by the US Intergroup 0116 study.

Between January 2010 and December 2014, 48 patients with localized gastric adenocarcinoma, managed at radiotherapy department of the national institut of oncology, they underwent adjuvant chemoradiation according the classical MacDonald regimen.

This series consisted of non-metastatic patients, 68.8% (33) males with a mean age 51 years. 20.8% (10) of patients had relapses (all distant relapse). 22 (45.8%) patients died, only 8(16.6%) patients were lost to follow up.

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Advanced Radiotherapy Techniques to Reduce Mortality and Morbidity in Cervical Cancer

Cervical cancer is the 4th major killer of the women worldwide. Despite primary and advanced medical care and awareness levels in most part of the developed worlds, the mortality remained very high till date.

If it is localized at the time of diagnosis, the five year survival rate would by 61% in UK and if it is in the metastatic, it guarantees only 44% survival rate. Chemotherapy, followed by the radio therapy is the usual treatment procedure for the cervical cancer. Yet it could not reduce the mortality and morbidity and it is leading to hematologic toxicity, the radiation is also affecting the health cells in the body.

Intensity Modulated Radiotherapy (IMRT) and image guided brachytherapy (IGBT) are the recent advancements, capable of strictly confining to the target area. Exciting therapeutic and pharmacological methods are ensuring the improved survival rates due to effective treatment procedures.

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Molecular Targets in Lung Cancer Therapy: A Current Review

Cancer incidence worldwide has been increasing over the years. Lung cancer (LC) is a disease with a poor prognosis once diagnosed. LC is the leading cause of death in men worldwide and the second cause of mortality in women . In Portugal, LC remains as the leading cause of deathdue cancer in men. 

LC origins from oncogenic alterations in tissues from the respiratory epithelium, namely in bronchi, bronchioles and alveoli. This cancer results from multiple morphological, molecular and genetic changes, leading to an accumulation of malignant cells. LC is mainly classified into two categories, according to its histological characteristics: non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC). NSCLC is categorized into three different categories, namely adenocarcinoma, squamous cell carcinoma and large cell carcinoma.  Read More>>>>>>

Exceptional Therapeutic Outcome of Metastatic Neuroendocrine Tumor with Peptide Receptor Radionuclide Therapy with Brief Review of Literature

NETs are rare, heterogeneous group of neoplasm presented as chronic oncologic disease. Somatostatin analogue is the standard first line systemic therapy for mainly hormone control.

No standard second line systemic treatment is available except everolimus which has no reported complete response.

PRRT is an innovative molecular targeted treatment based on theragnostic concept for well differentiated NETs. We presented here a 63-year-old lady with grade 1 NET of rectum with lymphnodal and liver metastasis.

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Sentinel Lymph Node Mapping and Dissection in Patients with Endometrial Cancer

In developed countries, endometrial cancer (EC) is the most frequent cancer of the female reproductive system.

According to the recent recommendations and guidelines, systematic surgical staging represents the primary treatment of these patients.

However, the extent of this procedure should be carefully individualized according to the histological type and the patient’s general performance status.

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Personalized Medicine is the Key to Effective Cancer Treatment

Cancer is a disease involving abnormal cell growth with the potential to invade or metastasize to other parts of the body. The most common types of cancer in males are lung cancer, prostate cancer, colorectal cancer, and stomach cancer, and in females, the most common types are breast cancer, colorectal cancer, lung cancer, and cervical cancer.

In children, acute lymphoblastic leukemia and brain tumors are the most common types of cancer.

The risk of cancer increases significantly with age in addition to the many other risk factors such as the use of tobacco, obesity, lack of physical activity, environmental pollutants, viruses and many others.

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