Because of the
many controversies concerning the consumption of antioxidants
during the treatment of cancer, herein we decided to ascertain whether the
supplementation of Beta vulgaris (strong antioxidant) in irradiated head and
neck cancer patients would influence parameters which describe oxidative
stress/DNA damage and the clinical effects of therapy.
Forty one
patients with head and neck cancer (T3-4 N1 M0) were divided into two
subgroups: I/supplementation chips from beetroot (n=19) and II/control group
(n=22). All the patients were eligible for radiotherapy.
Dische scale.
Total survival times were assessed together with oxidative DNA damage on the
level of the whole organism and whether the biomarkers of the damage such as
8-oxo-dG and its modified base (8-oxo-Gua) were present in urine and DNA.
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