The aim of this clinical study was to compare
breast-conserving therapy (BCT) and radical mastectomy (RM) in the treatment of
early breast cancer. Materials and methods: From March 1986 to the end of 1989,
117 women with a breast tumor of up to 2 cm in size were included in this
study; 66 women had a quadrantectomy, while 51 had a radical mastectomy.
Full axillary dissection was performed in all patients, while
adjuvant chemotherapy with cyclophosphamide, methotrexate and fluorouracil was
conducted in node-positive patients. Radiation to the remaining breast
parenchyma consisted of external-beam therapy, with or without regional
irradiation, without boost to the tumor bed. Results: The follow-up of patients
in the two treatment groups was limited to 240 months.
The mean period of observation (SD±) was 201.34 months (54.12
± 226.5) for the patients with breast-conserving therapy (BCT) and 195.84
months (35.1 ± 226.5) for the patients with radical mastectomy.
No comments:
Post a Comment