Following our review on leukemia and the nervous system we
would like to draw your attention to a rare manifestation of leukemia termed
historically chloroma (CH) or myelosarcoma, which can rarely affect the cranial
nerves and the peripheral nerves.
These rare associations of leukemia and the
peripheral nervous system, can occur in all stages of leukemia, as the first manifestation, as
recurrence and post bone marrow transplant. Most frequently CH are seen in AML,
less frequent CML, but also in OMF.
They can also appear isolated, and leave room for
speculations why leukemia can covert from a liquid into a solid tumor, and why
the presentation can be in peripheral nerves. Chloromas, myelosarcomas or
leukemic tumors are rare and present at many sites of the body. Compared to
lymphomas focal nerve lesion in leukemia are rare.
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