Hepatic carcinoma
(HCC) has rised in China because of hepatitis B virus(HBV) effection, it has
been famous for devastating malignancy as well as little treatment effect for
HCC Sorafenib, has been successfully applied for solid tumors such as renal
cancer, hepatocellular carcinoma.
Sorafenib used
alone or combination with others can induce growth-inhibition and apoptosis in
vitro experiment. Sorafenib now was suggested to advanced hepatic carcinoma
patient unqualitied for hepatectomy and transplant.
A team of
advanced hepatic carcinoma patients were enrolled for Sorafenib monotherapy or
combination with HIAC,TACE, systemtic chemotherapy with arsenic trioxide and
octreotide on base of personal disease progress CT and level of AFP were used
to assess the tumor effect for decision of next treatment plan, An
individualization treatment plan was performed ultimately.
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