Prostate cancer is the most prevalent solid
tumor diagnosed in men in developed countries. The standard treatment for early
stage prostate cancer is surgery (prostatectomy) or radiotherapy. To improve
local control, the radiation dose should be escalated.
Three dimensional conformal
radiation treatment (3DCRT) increases local control rates while decreasing
toxicity rates. Recent data suggest that, to achieve high local control of
prostate cancer with acceptable toxicity, hypofractionated
radiotherapy (HRT) could be used. Short-duration HRT is an attractive option compared with a
7-to-8-week course of standard radiotherapy in terms of logistics; the
patient’s job, daily activities, and emotions; the availability of
accelerators, and the cost of prolonged treatment.
Quality of life (QoL) has become
one of the most significant issues in treatment decisions in prostate cancer.
In the case of QoL measurement after radical prostatectomy, brachytherapy, or
external beam radiotherapy, all types of prostate cancer treatment were shown
to be associated with changes in the QoL domains related to urinary, bowel, and
sexual functions.
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