Chronic Myeloid Leukemia (CML) is a myeloproliferative
neoplasm typically diagnosed in adult population and relatively rare in
children with incidence of 0.6-1.2/ million per year. CML is a clonal disorder
of hematopoietic progenitor cells resulting from the balanced translocation
called Philadelphia chromosome (Ph) at molecular level resulting in formation
of a fusion gene BCR-ABL .
The BCR-ABL protein encoded by the fusion gene has an
activity of tyrosine kinase and promotes uncontrolled
proliferation of pluripotent stem cells in Bone Marrow (BM). CML has a
three-phase course: Chronic phase (CML-CP), accelerated phase (CML-AP) and
blast crisis phase.
CML is most commonly diagnosed in the CML-CP and only in
about 10% of cases in advanced phases: CML-AP or CML-BC.Before the
implementation of imatinib, hydroxyurea +/- interferon alpha remained the first
line treatment of CML, followed by HSCT after achievement of hematologic
remission. The identification of Tyrosine Kinase Inhibitors (TKI) with BCR-ABL
blocking ability revolutionized the CML therapy due to pharmacological control
of leukemic clone.
Irrespective of receiving daily oral or future injectable depot therapies, these require health care visits for medication and monitoring of safety and response. If patients are treated early enough, before a lot of immune system damage has occurred, life expectancy is close to normal, as long as they remain on successful treatment. However, when patients stop therapy, virus rebounds to high levels in most patients, sometimes associated with severe illness because i have gone through this and even an increased risk of death. The aim of “cure”is ongoing but i still do believe my government made millions of ARV drugs instead of finding a cure. for ongoing therapy and monitoring. ARV alone cannot cure HIV as among the cells that are infected are very long-living CD4 memory cells and possibly other cells that act as long-term reservoirs. HIV can hide in these cells without being detected by the body’s immune system. Therefore even when ART completely blocks subsequent rounds of infection of cells, reservoirs that have been infected before therapy initiation persist and from these reservoirs HIV rebounds if therapy is stopped. “Cure” could either mean an eradication cure, which means to completely rid the body of reservoir virus or a functional HIV cure, where HIV may remain in reservoir cells but rebound to high levels is prevented after therapy interruption.Dr Itua Herbal Medicine makes me believes there is a hope for people suffering from,Parkinson's disease,Schizophrenia,Lung Cancer,Breast Cancer,Lupus,Lymne Disease,psoriasis,Colo-Rectal Cancer,Blood Cancer,Prostate Cancer,siva,Epilepsy Dupuytren's disease,Desmoplastic small-round-cell tumor Diabetes ,Coeliac disease,Brain Tumor,Fibromyalgia,Alzheimer's disease,Adrenocortical carcinoma Infectious mononucleosis. .Asthma,Allergic diseases.Hiv_ Aids,Herpe ,Copd,Glaucoma., Cataracts,Macular degeneration,Cardiovascular disease,Chronic Myelo ,Lung disease,Enlarged prostate,Osteoporosis,Dementia.(measles, tetanus, whooping cough, tuberculosis, polio and diphtheria),Chronic Diarrhea,Hpv,All Cancer Types,Diabetes,Hepatitis, I read about him online how he cure Tasha and Tara so i contacted him on drituaherbalcenter@gmail.com / . even talked on whatsapps +2348149277967 believe me it was easy i drank his herbal medicine for two weeks and i was cured just like that isn't Dr Itua a wonder man? Yes he is! I thank him so much so i will advise if you are suffering from one of those diseases Pls do contact him he's a nice man.
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